Guang-Zhong Wang, Ph.D.
Decoding the Transcriptome of Behavior: from Yeast to Human Brain.
Mini-symposium on Imaging Neuronal and Circuit Dynamics
Institute of Neuroscience
As part of a major drive for excellence in basic research in the new millennium, the Chinese Academy of Sciences founded the Institute of Neuroscience (ION) on November 27, 1999. The ......
In vivo monitoring of dopamine release in a transparent brain
In a recent study, Dr. DU Jiulin’s lab found that Dopamine release can be evoked by a hedonic olfactory stimulus, monitored in real time, and traced to its circuit origin in the transparent brain of zebrafish larvae. This work demonstrated for the first time that sensory-evoked dopamine release can be successfully monitored in the brain of an awake small organism.....
TRPC6 Specifically Inhibits Aβ Production
In a recent study, researchers at the Institute of Neuroscience, reported that Transient receptor potential canonical (TRPC) 6 blocked the interaction between APP and γ-secretase to specifically suppress Aβ production. TRPC6 specifically interacts with APP (C99), but not with Notch, and prevents C99 interaction with presenilin 1 (PS1), leading to i....
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