论文
| • Qiu, P#., Jiang, J#., Liu, Z#., Cai, Y., Huang, T., Wang, Y., Liu, Q., Nie, Y., Liu, F., Cheng, J., Li, Q., Tang, Y-C., Poo, M-m., Sun, Q*., and Chang, H-C*. #: Equal contribution *: Corresponding author (2019) BMAL1 knockout macaque monkeys display reduced sleep and psychiatric disorders Natl Sci Rev 6: 87-100 |
| • Liu, Z#*., Cai,Y#., Liao, Z#., Xu, Y., Wang, Y., Wang, Z., Jiang, X., Li, Y., Lu, Y., Nie, Y., Zhang,X., Li, C., Bian, X., Poo, M-m., Chang, H-C*., and Sun, Q*. #: Equal contribution *: Corresponding author (2019) Cloning of a gene-edited macaque monkey by somatic cell nuclear transfer. Natl Sci Rev 6: 101-108 |
| • Jiang, X., Zhang, T., Wang, H., Wang, T., Qin, M., Bao, P., Wang, R., Liu, Y., Chang, H-C., Yan, J., and Xu, J. (2018) Neurodegeneration-associated FUS is a novel regulator of circadian gene expression. Transl Neurodegener 12: 24 |
| • Zhang, T., Jiang, X., Xu, M., Wang, H., Sang, X., Qin, M., Bao, P., Wang, R., Zhang, C., Lu, H., Li, Y., Ren, J., Chang, H-C., Yan, J., Sun, Q., and Xu, J. (2018) Sleep and circadian abnormalities precede cognitive deficits in R521C FUS knockin rats. Neurobiol Aging 72: 159-170 |
| • Liu, F., and Chang, H-C (2017) Physiological links of circadian clock and biological clock of aging. Protein Cell 8: 477-488 |
| • Jia, XE., Ma, K., Xu, T., Gao, L., Wu, S., Fu, C., Zhang, W., Wang, Z., Liu, K., Dong, M., Jing, C., Ren, C., Dong, Z., Chen, Y., Jin, Y., Huang, Q., Chang, X., Deng, M., Li, L., Luo, L., Zhu, J., Dang, Y., Chang, H-C., Zon, L.I., Zhou, Y., Chen, S., Pan, W. (2015) Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell Res. 25: 946-962 |
| • Chang, H-C., and Guarente, L. (2014) SIRT1 and other sirtuins in metabolism. Trends Endocrinol Metab. 25: 138-145 |
| • Chang, H-C., and Guarente, L.P. (2013) SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging. Cell 153: 1448-1460 |
| • Calloni,G., Chen, T., Schermann, S. M., Chang, H-C., Genevaux, P., Agostini, F., Tartaglia, G.G., Hayer-Hartl, M., and Hartl, F.U. (2012) DnaK Functions as a Central Hub in the E. coli Chaperone Network. Cell Rep. 1: 251–264 |
| • Gupta, R., Lakshmipathy, S.K., Chang, H-C., Etchells, S.A., and Hartl, F.U. (2010) Trigger factor lacking the PPIase domain can enhance the folding of eukaryotic multi-domain proteins in Escherichia coli. FEBS Lett. 584: 3620-3624 |
| • Tang, Y-C#., Chang, H-C#., Chakraborty, K., Hartl, F.U., and Hayer-Hartl, M. (2008) Essential role of the chaperonin folding compartment in vivo. EMBO J. 27: 1458-1468 |
| • Chang, H-C., Tang, Y-C., Hayer-Hartl, M., and Hartl, F. U. (2007) SnapShot: Molecular Chaperones, Part I Cell 128: 212 |
| • Tang, Y-C., Chang, H-C., Hayer-Hartl, M., and Hartl, F. U. (2007) SnapShot: Molecular Chaperones, Part II. Cell 128: 412 |
| • Lakshmipathy, S.K., Tomic, S., Kaiser, C.M., Chang, H-C., Genevaux, P., Georgopoulos, C., Barral, J.M., Johnson, A.E., Hartl, F.U., and Etchells, S.A. (2007) Identification of nascent chain interaction sites on trigger factor. J Biol Chem 282: 12186-12193 |
| • Kaiser, C. M., Chang, H-C., Agashe, V. R., Lakshmipathy, S. K., Etchells, S. A., Hayer-Hartl, M., Hartl, F. U., and Barral, M. (2006) Real-time observation of trigger factor function on translating ribosomes. Nature 444: 455-460 |
| • Tang, Y-C., Chang, H-C., Roeben, A., Wischnewski, D., Wischnewski, N., Kerner, M. J., Hartl, F. U., and Hayer-Hartl, M. (2006) Structural features of the GroEL-GroES nano-cage required for rapid folding of encapsulated protein Cell 125: 903-914 |
| • Chang, H-C., Kaiser, C. M., Hartl, F. U., and Barral, J. M. (2005) De novo folding of GFP fusion proteins: high efficiency in eukaryotes but not in bacteria. J Mol Biol 353: 397-409 |
| • Kerner, M. J#., Naylor, D. J#., Ishihama, Y#., Maier, T#., Chang, H-C., Stines, A.P., Georgopoulos, C., Frishman, D., Hayer-Hartl, M., Mann, M., and Hartl, F. U. #: Equal contribution (2005) Proteome-wide analysis of chaperonin-dependent protein folding in Escherichia coli. Cell 122: 209-220 |
| • Shomura, Y., Dragovic, Z., Chang, H-C., Tzvetkov, N., Young, J. C., Brodsky, J. L., Guerriero, V., Hartl, F. U., and Bracher, A. (2005) Regulation of Hsp70 function by HspBP1: structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange. Mol Cell. 17: 367-379 |
| • Agashe, V. R#., Guha, S#., Chang, H-C#., Genevaux, P., Hayer-Hartl, M., Stemp, M., Georgopoulos, C., Hartl, F. U., and Barral, J. M. #: Equal contribution (2004) Function of trigger factor and DnaK in multidomain protein folding: increase in yield at the expense of folding speed. Cell 117: 199-209 |
