代表性论文
| • Peibo Xu *，Jian Peng，Tingli Yuan，Zhaoqin Chen，Hui He，Ziyan Wu，Ting Li，Xiaodong Li，Luyue Wang，Le Gao，Jun Yan，Wu Wei，Chengyu T. Li*，Zhen-Ge Luo*，Yuejun Chen*. (2024) High-throughput mapping of single-neuron projection and molecular features by retrograde barcoded labeling. eLife e: 85419. |
| • Lianshun Xie, Hengxin Liu, Zhiwen You, Luyue Wang, Yiwen Li, Xinyue Zhang, Xiaoshan Ji, Hui He, Tingli Yuan, Wenping Zheng, Ziyan Wu, Man Xiong, Wu Wei*,Yuejun Chen*. (2023) Comprehensive spatiotemporal mapping of single-cell lineages in developing mouse brain by CRISPR-based barcoding. Nature Methods 20: 1244-1255. |
| • Zhiwen You, Luyue Wang, Hui He, Ziyan Wu, Xinyue Zhang, Shuaixiang Xue, Peibo Xu, Yanhong Hong, Man Xiong, Wu Wei*,Yuejun Chen*. (2023) Mapping of clonal lineages across developmental stages in human neural differentiation Cell Stem Cell 30: 473-487 (Cover Story) . |
| • Xiaoli Ji, Yingying Zhou, Qinqin Gao, Hui He, Ziyan Wu, Ban feng, Yuting Mei, Yan Cheng, Wenhao Zhou*, Yuejun Chen*, Man Xiong*. (2023) Functional reconstruction of the basal ganglia neural circuit by human striatal neurons in hypoxic–ischaemic injured brain. Brain 146: 612-628. |
| • Peibo Xu, Hui He, Qinqin Gao, Yingying Zhou, Ziyan Wu, Xiao Zhang, Linyu Sun, Gang Hu, Qian Guan, Zhiwen You, Xinyue Zhang, Wenping Zheng, Man Xiong, and Yuejun Chen* (2022) Human midbrain dopaminergic neuronal differentiation markers predict cell therapy outcome in a Parkinson’s disease model. Journal of Clinical Investigation 132: e156768. |
| • Man Xiong, Yezheng Tao, Qinqin Gao, Ban Feng, Wei Yan, Yingying Zhou, Thomas A. Kotsonis, Tingli Yuan, Zhiwen You, Ziyan Wu, Jiajie Xi, Alexander Haberman, Julia Graham, Jasper Block, Wenhao Zhou, Yuejun Chen*and Su-Chun Zhang. (2021) Human Stem Cell-Derived Neurons Repair Circuits and Restore Neural Function. Cell Stem Cell 28: 112-126. |
| • Yuejun Chen*, Man Xiong, Yi Dong, Alexander Haberman，Jingyuan Cao, Huisheng Liu, and Su-Chun Zhang*. (2016) Chemical Control of Grafted Human PSC-Derived Neurons in a Mouse Model of Parkinson’s Disease. Cell Stem Cell. 18: 817-826. |
| • Yuejun Chen*, Jingyuan Cao, Man Xiong, Andrew J. Petersen, Yi Dong, Yunlong Tao, Cindy Tzu-Ling Huang, Zhongwei Du, and Su-Chun Zhang*. (2015) Engineering Human Stem Cell Lines with Inducible Gene Knockout using CRISPR/Cas9 Cell Stem Cell 17: 233-244 |
| • Yuejun Chen, Man Xiong, Suchun Zhang*. (2015) Illuminating Parkinson's therapy with optogenetics Nat. Biotechnol. 33: 149-150 |
论文
| • Ran Zhang, Hui He, Bo Yuan, Ziyan Wu, Xiuzhen Wang, Yasong Du*,Yuejun Chen*, Zilong Qiu*. (2021) An Intronic Variant of CHD7 Identified in Autism Patients Interferes with Neuronal Differentiation and Development. Neuroscience Bulletin 37(8): 1091-1106. |
| • Hui Long, Xinru Zhu, Ping Yang, Qinqin Gao,Yuejun Chen* , Lan Ma*. (2013) Myo9b and RICS modulate dendritic morphology of cortical neurons Cereb Cortex 23(1): 71-79 |
| • Ziyan Wu, Yuejun Chen*, Tong Yang, Qinqin Gao, Man Yuan, Lan Ma. (2012) Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex Plos One 7(8): e43997 |
| • Yuejun Chen, Feifei Wang, Hui Long, Ying Chen, Ziyan Wu, Lan Ma*. (2011) GRK5 promotes F-actin bundling and targets bundles to membrane structures to control neuronal morphogenesis J. Cell. Biol. 194(6): 905-920 |
| • Yuejun Chen, Yan Jiang, Wen Yue, Yuqing Zhou, Lin Lu, Lan Ma*. (2008) Chronic, but not acute morphine treatment, up-regulates α-Ca2+/calmodulin dependent protein kinase II gene expression in rat brain. Neurochem Res. 33(10): 2092-8. |
| • Yuejun Chen, Hui Long, Ziyan Wu, Xi Jiang, Lan Ma*. (2008) EGF transregulates opioid receptors through EGFR-mediated GRK2 phosphorylation and activation Mol. Biol. Cell 19: 2973-83 |
| • Shibo Xu, Xinrui Li, Pan Fan, Xiyang Li, Yuan Hong, Xiao Han, Shanshan Wu, Chu Chu, Yuejun Chen, Min Xu, Mingyan Lin*, Xing Guo*, Yan Liu*. (2024) Single-Cell Transcriptome Landscape and Cell Fate Decoding in Human Brain Organoids after Transplantation. Adv Sci (Weinh). : e2402287. |
| • Xinyao Sun, Xiangchun Ju *, Yang Li, Peng ming Zeng, Jian Wu, Yingying Zhou, Libing Shen, Jian Dong,Yuejun Chen (2022) Generation of vascularized brain organoids to study neurovascular interactions eLife. 2022: e76707. |
| • Yunlong Tao, Scott C Vermilyea , Matthew Zammit , Jianfeng Lu , Miles Olsen , Jeanette M Metzger , Lin Yao ,Yuejun Chen, Sean Phillips , James E Holden , Viktoriya Bondarenko , Walter F Block , Todd E Barnhart , Nancy Schultz-Darken , Kevin Brunner , Heather Simmons , Bradley T Christian , Marina E Emborg*, Su-Chun Zhang*. (2021) Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys. Nat Med. 27(4): 632-639. |
| • Xin Dong, Shi-Bo Xu, Xin Chen, Mengdan Tao, Xiao-Yan Tang, Kai-Heng Fang, Min Xu, Yufeng Pan, Yuejun Chen, Shuijin He*, Yan Liu*. (2020) Human cerebral organoids establish subcortical projections in the mouse brain after transplantation. Mol Psychiatry 26: 2964-2976. |
| • Yi Dong*, Man Xiong,Yuejun Chen, Yezheng Tao , Xiang Li , Anita Bhattacharyya , Su-Chun Zhang *. (2020) Plasticity of Synaptic Transmission in Human Stem Cell-Derived Neural Networks. iScience. 23(2): 100829. |
| • Fang Yuan, Xin Chen, Kaiheng Fang, Yuanyuan Wang, Mingyan Lin, Shibo Xu, Haiqin Huo, Min Xu, Lixiang Ma,Yuejun Chen, Shuijin He*, Yan Liu*. (2018) Induction of human somatostatin and paravalbumin neurons by expressing a single transcription factor LIM homeobox 6. eLife, : 37382. |
| • Qiumin Le*,Wenqing Yao,Yuejun Chen., Biao Yan, Cao Liu, Man Yuan, Yuqing Zhou, Lan Ma*. (2016) GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal. Cell Death Dis. 7(11): e2478. |
| • Yezheng Tao, Li Ma, Zhaohui Liao, Qiumin Le, Jialing Yu, Xing Liu, Haohong Li,Yuejun Chen, Ping Zheng, Zhengang Yang, Lan Ma*. (2015) Astroglial β-Arrestin1-mediated Nuclear Signaling Regulates the Expansion of Neural Precursor Cells in Adult Hippocampus. Sci Rep. 5: 15506. |
| • Qinqin Gao, Wenqing Yao, Junjun Wang, Tong Yang, Cao Liu, Yezheng Tao, Yuejun Chen, Xing Liu,* Lan Ma*. (2015) Post-training activation of Rac1 in the basolateral amygdala is required for the formation of both short-term and long-term auditory fear memory. Front Mol Neurosci. 8: 65. |
| • Kun Qian, Cindy Tzu-Ling Huang, Hong Chen, Lisle W Blackbourn 4th,Yuejun Chen, Jingyuan Cao, Lin Yao, Cornall Sauvey, Zhongwei Du*, Su-Chun Zhang*. (2014) A simple and efficient system for regulating gene expression in human pluripotent stem cells and derivatives. Stem Cells 32(5): 1230-8. |
| • Junjun Wang, Wenqing Yao,Yuejun Chen, Lan Ma, Yezheng Tao*. (2014) Neurons in NAc core and BLA are activated during cocaine context-associated reward memory retrieval in mice. Sheng Li Xue Bao. 66(5): 545-58. |
| • Chi Xu, Minhua Hong, Le-Sha Zhang, Yuanyuan Hou, Yuhua Wang, Feifei Wang, Yuejun Chen, Xuejun Xu, Jie Chen, Xin Xie, Lan Ma, Zhiqiang Chi, Jinggen Liu*. (2010) Serine 363 of the δ-opioid receptor is crucial for adopting distinct pathways to activate ERK1/2 in response to stimulation with different ligands. J Cell Sci. 123(Pt 24): 4259-70. |
| • Xiaoqing Zhang, Feifei Wang, Xiaoqing Chen,Yuejun Chen, Lan Ma*. (2008) Post-endocytic fates of δ-opioid receptor are regulated by GRK2-mediated receptor phosphorylation and distinct β-arrestin isoforms. J Neurochem. 106(2): 781-92. |
| • Jingxia Gao, Jiali Li,Yuejun Chen, Lan Ma*. (2005) Activation of tyrosine kinase of EGFR induces Gβγ-dependent GRK-EGFR complex formation. FEBS Lett. 579(1): 122-126. |
