 A Role of Autophagy in Regulating Axonal Development |
(2017-8-25) |
| A recent study published in Autophagy demonstrated that Mir505-3p regulated axonal development by targeting Atg12 and autophagy pathway. This work was performed by researchers in Dr. ZHOU Yuxun’s team at the Donghua University and Dr. QIU Zilong’s Lab at the Institute of Neuroscience, Chinese Academy of Sciences.This work provided another evidence supporting the role of autophagy in neural development. |
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| Pre-synaptic Cadherin/Catenin Complexes Drive Post-Synaptic Dendritic Spine Stabilization in vivo |
(2017-6-22) |
| A recent study entitled “A critical role of pre-synaptic cadherin/catenin/p140Cap complexes in stabilizing spines and functional synapses in the neocortex” from Dr. YU Xiang’s lab at the Institute of Neuroscience, Chinese Academy of Sciences was published in Neuron on June 21, 2017. The effect of the cadherin/catenin requires p140Cap —— a novel β-catenin interacting partner. |
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| Embryonic Origin of Retinal Stem Cells |
(2017-5-3) |
| Using zebrafish and cytobow-based clonal analysis, Dr HE Jie's team identified the cells in the second or the third layer of the CMZ as the RSCs which were slow-cycling as compared to retina progenitors in CMZ. Moreover, the study also identified a novel set of dormant CMZ tip cells, which may serve as a critical cellular component in the niche. |
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| Neurons Regulate Brain Vascular Integrity by Secreting Exosomes |
(2017-4-24) |
| A recent study published online in Cell Research reported that neurons transfer miR-132 into brain vascular endothelial cells (ECs) via exosomes to promote brain vascular integrity. This study was performed by Dr. DU Jiulin’s research group in the Institute of Neuroscience and the Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences. |
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| Researchers Reveal the Role of Long Noncoding RNAs in Circadian Gene Regulation |
(2017-4-7) |
| A recent study by Dr. YAN Jun’s lab at the Institute of Neuroscience, Chinese Academy of Sciences, was published in Nucleic Acids Research on March 8. It uncovered that a class of enhancer-associated circadian long noncoding RNAs (lncRNAs) mark the genomic loci modulating long-range circadian gene regulation. |
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| Functional Circuits Regulating the Activity of Serotonergic Neurons |
(2017-3-22) |
| A recent study published in Cell Reports systematically analyzed the circuit mechanism underlying dynamic control of serotonergic neuron in the rodent brain. This work was performed by researchers in Dr. SUN Yangang’s Lab. This work advanced our understanding of the mechanisms regulating the serotonin system, which could have important impact on studying the mechanisms of mental disorder. |
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| FGF13 Acts as a Selective Regulator of Heat Nociception |
(2017-2-3) |
| A recent study published in Neuron shows that fibroblast growth factor 13 (FGF13) plays a critical role in the regulation of heat nociception. This research work was carried out by Dr. ZHANG Xu’s Lab at the Institute of Neuroscience, Chinese Academy of Sciences. |
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