Laboratory of
Neural Circuit and Sensory Processing
All Publications
1.Gao ZR, Chen WZ, Liu MZ, Chen XJ, Wan L, Zhang XY, Yuan L, Lin JK, Wang M, Zhou L, Xu XH, Sun YG*. (2019) Tac1-expressing neurons in the periaqueductal gray facilitate the itch-scratching cycle via descending regulation. Neuron 101:45-59.
2.Yuan L, Liang TY, Deng J, Sun YG*. (2018) Dynamics and functional role of dopaminergic neurons in the ventral tegmental area during itch processing. J Neurosci. 38:9856-9869.
3.Mu D, and Sun YG* (2017) Itch induces conditioned place aversion in mice. Neurosci. Lett. 658: 91-96.
4.Mu D, Deng J, Liu KF, Wu ZY, Shi YF, Guo WM, Mao QQ, Liu XJ, Li H, Sun YG*. (2017) A central neural circuit for itch sensation. Science 357:695-699.
5.Zhou L, Liu MZ, Li Q, Deng J, Mu D, Sun YG (2017) Organization of Functional Long-Range Circuits Controlling the Activity of Serotonergic Neurons in the Dorsal Raphe Nucleus. Cell Rep. 18:3018-3032.
6.Yang Y, Liu DQ, Huang W, Deng J, Sun YG, Zuo Y & Poo MM. (2016) Selective synaptic remodeling of amygdalocortical connections associated with fear memory. Nat. Neurosci. 19:1348-1355.
7.Sun YG, Rupprecht V, Zhou L, Dasgupta R, Seibt F, Beierlein M (2016) mGluR1 and mGluR5 synergistically control cholinergic synaptic transmission in the thalamic reticular nucleus. J Neurosci. 36:7886-7896.
8.Barry DM, Li H, Liu XY, Shen KF, Liu XT, Wu ZY, Munanairi A, Chen XJ, Yin J, Sun YG, Li YQ, Chen ZF. (2016) Critical evaluation of the expression of gastrin-releasing peptide in dorsal root ganglia and spinal cord. Mol Pain. 2016 Apr 11;12.
9.Zhao ZQ, Liu XY, Jeffry J, Karunarathne WK, Li JL, Munanairi A, Zhou XY, Li H, Sun YG, Wan L, Wu ZY, Kim S, Huo FQ, Mo P, Barry DM, Zhang CK, Kim JY, Gautam N, Renner KJ, Li YQ, Chen ZF. (2014) Descending control of itch transmission by the serotonergic system via 5-HT1A-facilitated GRP-GRPR signaling. Neuron 84: 821-34.
10.Zhang Y, Qin WJ, Qian ZY, Liu XJ, Wang H, Gong S, Sun YG*, Snutch TP, Jiang XH, Tao J*. (2014) Peripheral pain is enhanced by insulin-like growth factor 1 through a G protein-mediated stimulation of T-type calcium channels. Sci Signal. 7(346):ra94.
11.Sun YG, Pita-Almenar JD, Wu CS, Renger JJ, Uebele VN, Lu HC, Beierlein M. (2013) Biphasic cholinergic synaptic transmission controls action potential activity in thalamic reticular nucleus neurons. J Neurosci. 33:2048-59.
12.Sun YG, Wu CS, Renger J, Uebele V, Lu HC, Beierlein M. (2012) GABAergic synaptic transmission triggers action potentials in thalamic reticular nucleus neurons. J Neurosci. 32:7782-90.
13.Sun YG, Wu CS, Lu HC, Beierlein M. (2011) Target-dependent control of synaptic inhibition by endocannabinoids in the thalamus. J Neurosci. 31:9222-30.
14.Sun YG, Beierlein M. (2011) Receptor saturation controls short-term synaptic plasticity at corticothalamic synapses. J Neurophysiol. 105:2319-29.
15.Liu XY, Liu ZC, Sun YG, Ross M, Kim S, Tsai FF, Li QF, Jeffry J, Kim JY, Loh HH, Chen ZF. (2011) Unidirectional cross activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids. Cell. 147:447-458.
16.Sun YG, Zhao ZQ, Meng XL, Yin J, Liu XY, Chen ZF. (2009) Cellular basis of itch sensation. Science, 325:1531-4.
17.Sun YG, Gracias NG, Drobish J, Vasko MR, Gereau RW, Chen ZF. (2009) The c-kit signaling pathway is involved in the development of persistent pain. Pain 144:178-86.
18.Sun YG, Gao YJ, Zhao ZQ, Huang B, Yin J, Taylor GA, Chen ZF. (2008) Involvement of P311 in the affective, but not in the sensory component of pain. Mol Pain 4:23.
19.Sun YG, Chen ZF. (2007) A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord. Nature 448:700-703.
20.Zhao ZQ, Gao YJ, Sun YG, Zhao CS, Gereau RW, Chen ZF. (2007) Central serotonergic neurons are differentially required for opioid analgesia but not for morphine tolerance or morphine reward. Proc Natl Acad Sci USA. 104: 14519ĘC14524.
21.Zhao ZQ, Chiechio S, Sun YG, Zhang KH, Zhao CS, Scott M, Johnson RL, Deneris ES, Renner KJ, Gereau RW, Chen ZF. (2007) Mice lacking central serotonergic neurons show enhanced inflammatory pain and an impaired analgesic response to antidepressant drugs. J Neurosci. 27: 6045-6053.
22.Gu XL, Sun YG, Yu LC. (2007) Involvement of galanin in nociceptive regulation in the arcuate nucleus of hypothalamus in rats with mononeuropathy. Behav Brain Res. 179:331-335.
23.Sun YG, Gu XL, Yu LC. (2007) The neural pathway of galanin in the hypothalamic arcuate nucleus of rats: activation of beta-endorphinergic neurons projecting to periaqueductal gray matter. J Neurosci Res. 85:2400-2406.
24.Sun YG, Yu LC (2005) Interactions of galanin and opioids in nociceptive modulation in the arcuate nucleus of hypothalamus in rats. Regul Pept. 124:37-43.
25.Sun YG, Li J, Yang BN, Yu LC (2004) Antinociceptive effects of galanin in the rat tuberomammillary nucleus and the plasticity of galanin receptor 1 during hyperalgesia. J Neurosci Res. 77:718-722.
26.Sun YG, Lundeberg T, Yu LC (2003) Involvement of endogenous beta-endorphin in antinociception in the arcuate nucleus of hypothalamus in rats with inflammation. Pain 104: 55-63.
27.Sun YG, Gu XL, Lundeberg T, Yu LC (2003) An antinociceptive role of galanin in the arcuate nucleus of hypothalamus in intact rats and rats with inflammation. Pain 106: 143-150.
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